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In some embodiments, following the isolation of the microspheres from the continuous-phase processing medium, the remainder of the solvent in the microspheres is removed by extraction

A time-course experiment showed maximal labeling of acetyl-CoA in DKO cells within 2 hours, reaching up to 30% (Supplemental Figure 5A)

Only in the presence of clinical signs suggesting an underlying disorder (malabsorption, chronic losses, or inadequate nutrition) should additional studies be considered.3,6 Physiological nail findings

While capsules can be administered by mouth to pigs, it was decided to introduce the capsule directly into the jejunum, since the gastric transit in the pig can be variable and of long duration, the pig stomach is more fermenting than that of a human, and the pH of the stomach is high, to the extent that enteric coating of the capsule may not give adequate protection